The THD measurement in baseband mode does work in the whole frequency range, although it's of really no use past 20 Mhz signals as any harmonic would be out of the captured bandwidth.
Additionally, the low-pass and high-pass filters available for measurement configuration are intended for audio frequencies up to 80 kHz and down to 50 Hz.
So yes, the option 10 audio measurements are usable in baseband mode beyond the audio range, but their usefulness may be limited by the acquisition system.